Abu Dhabi (Urdu Point / Pakistan Point News / WAM – 02 April 2026) A team of researchers from New York University Abu Dhabi And university Denver has identified a promising small molecule that could help slow or halt the progression of serious brain diseases such as Parkinson’s, providing new hope for treatments that go beyond simply managing symptoms.
In the new study published in the journal Science Translational Medicine, Majzoub’s laboratory at New York University Abu Dhabi And Kumar Laboratory at the University of DenverTogether with international collaborators, it has developed a special type of small molecules designed to prevent this harmful buildup. The molecule, known as SK-129, works by blocking the protein from They clump and spread in the brain.
The team tested SK-129 across a wide range of disease models, including human cells, patient-derived tissues and organisms.
in everyone In cases, the molecule reduced the harmful effects associated with the disease.
Importantly, the researchers also showed that SK-129 can cross the blood-brain barrier, a protective layer that often prevents… Drugs from Access to the brain. In mouse models, the molecule significantly reduced the progression of disease-related damage in the brain.
“This is an important step toward developing treatments that target the root cause of these diseases,” NYU said. Abu Dhabi Associate Professor of Biology and co-author Mazen Majzoub. “Instead of just treating the symptoms, we work to slow or stop the disease itself.”